... a fantastic research and training environment on intrinsically disordered proteins!!!

Recent evidence shows that a large share of proteins gain functional advantages by remaining natively unstructured, either completely or partially, thus challenging well-established concepts in structural biology. In this frame NMR plays a strategic role to characterize at atomic resolution the highly dynamical properties of such “intrinsically disordered proteins”, and follow their (possible) reorganization by interacting with partners in environments as complex as whole cells. In order to achieve the full potential of this approach current methods should be further developed and properly interfaced with other complementary techniques. The purpose of our network is thus to establish a framework to train a new generation of young researchers in this emerging area. Understanding the functional role of intrinsically disordered protein states, which are involved in many biochemical processes at the basis of life, is expected to have a significant impact in biomedical research and in the design of new drugs.