IDPbyNMR workshop "Looking at intrinsically disordered proteins through NMR: challenges and perspectives"
June 30th, Creta Maris Hotel, Hersonissos, Crete, Greece
The EUROMAR in Crete provides an ideal opportunity to discuss about how NMR can contribute to the study of intrinsically disordered proteins that thanks to their high extent of disorder and flexibility are challenging well accepted concepts in structural biology. In the spirit of the IDPbyNMR Marie Curie ITN, the PhD students and post-docs will have an active role in the discussion by presenting their results as well as the challenges they are encountering in their research.
10.00-10.10 | Roberta Pierattelli, CERM, University of Florence, Italy Opening and introduction to the workshop |
10.10-10.30 | Sergio Gil, Bruker BioSpin AG, Fällanden, Switzerland Evaluating the contributions to 1H longitudinal relaxation enhancement through 13C detected experiments for the investigation of intrinsically disordered proteins |
10.30-10.50 | Tomáš Hošek, CERM, University of Florence, Italy NMR studies of IDPs at near physiological conditions: exploiting fast hydrogen exchange to boost experimental sensitivity |
10.50-11.10 | Anna Zawadzka-Kazimierczuk, University of Warsaw, Poland An optimal set of multidimensional experiments for resonance assignment of intrinsically disordered proteins |
11.10-11.30 | Jiří Nováček, Masaryk University, Brno, Czech Republic Transient local conformations of a 49kDa intrinsically disordered protein determined by NMR |
11.30-11.50 | Coffe break |
11. 50-12.10 | Guillaume Communie, IBS and UVHCI, Grenoble, France Order and disorder in the replication machinery of Paramyxoviruses |
12.10-12.30 | Pryanka Joshi, University of Cambridge, UK Towards a fragment based drug design strategy to design small molecules as inhibitors of Abeta aggregation |
12.30-12.50 | François Theillet, FMP Berlin, Germany In-cell dynamics, interactions and structural features of the human amyloidogenic protein alpha-synuclein |
12.50-13.20 | Miquel Pons, University of Barcelona, Spain Round Table and Brainstorming on NMR and IDPs |
13.20-13.30 | Isabella C. Felli, CERM, University of Florence, Italy Closing remarks |
13.30-14.00 | Lunch snacks |