Intensive Training Module 2012: 
Protein Structure Analysis using NMR Chemical Shifts

Cambridge, May 2-3, 2012
University of Cambridge, Cambridge, United Kingdom


ucam

Report on the ITM and participant list 

This course is aimed to develop an understanding and applications of the computational and experimental structural technique of NMR chemical shifts to analyse protein secondary and tertiary structures. It includes practical hands-on sessions.

Intrinsically disordered proteins (IDPs) are widespread in nature, as they play a variety of significant biological roles. However, to date, they have not been characterized structurally in much detail. Recent efforts in NMR spectroscopy have started to uncover the breadth of their conformational space. Chemical shifts, which are the most readily and accurately measurable NMR parameters, can be used for detection of transiently formed structure in intrinsically disordered proteins. This strategy, which is widely applicable, enables quantitative structural analysis to be carried out to address a range of complex biological problems.

Organizing Committe:
Michele Vendruscolo (UCAM)
Andrea Cavalli (UCAM)

Program:

May 2nd
9.00-12.00 pm      
Lecture: Molecular Dynamics Simulations
12.00-2.00 pm Lunch and Discussions
2.00-6.00 pm Practical Session: How to use the Cheshire Method
May 3rd
9.00-12.00 pm Lecture: Protein Structure Determination using Chemical Shifts
12.00-2.00 pm Lunch and Discussions
2.00-6.00 pm Practical Session: How to use the CamShift method


 

 

 

 



A more detailed program will be published as available.

 

Regarding Travel
There are 4 airports which connect London to Cambridge by either train or coach. The closest airport is Stansted (half an hour from Cambridge). You can also travel from either Heathrow (3 hours), Gatwick (4 hours) or Luton (1.5 hours). You can book your coach tickets via National Express http://www.nationalexpress.com/home.aspx or National Rail http://www.nationalrail.co.uk/

 

How to Apply

This Intensive Trainin Course designed for the training program of the EC Initial Training Network IDPbyNMR.
To apply you should send an e-mail to  info@idpbynmr.eu indicating the following:

  • Full name (name, last name)
  • Birth date
  • Nationality
  • Affiliation
  • Current position (PhD/post-doc)
  • Brief abstract of your current research (max 1/2 A4 size page)
  • List of publications
  • Letter of support by your supervisor.

Selected applicants will have to cover their travel, living expences and pay registration fee.

 

Best moments:

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Video from the event: