Priyanka Joshi


I have done my 5 Years Integrated M.Sc. in Biotechnology with Bioinformatics as an additional subject from Institute of Bioinformatics and Biotechnology (IBB), University of Pune, India. As part of my integrated course I completed two thesis during the 5 year period, one on the Pathway analysis of Acinetobacter baylyi: A combined bioinformatics and genomics approach at IBB, University of Pune, India, and the second on the Phylogenetic analysis of HIV-1 Subtype C at Centre for Cellular and Molecular Biology, Hyderabad, India. During the summers of 2009 and 2011, as a summer fellow of the Indian Academy of Sciences, I worked in Jawaharlal Nehru University, New Delhi, India, to study the host-parasite interaction in Leishmaniasis using a molecular biology and proteomics approach. Also, during the summer of 2010, I was a visiting undergraduate student in the Korbel Lab at EMBL, Heidelberg where I studied structural variations in yeast. In 2010, I was a recipient of a travel award from UCSD to present my undergraduate research in drug design at the RECOMB BE conference. I have also been the recipient of an entrepreneurship award from the Department of Biotechnology, Government of India for a research based business proposal on oral insulin.



Priyanka Joshi
Project Topic
Rational drug design on IDPs using NMR-derived structural ensembles.
Project Description
In this project, a novel strategy for the therapeutic treatment of neurodegenerative diseases will be investigated by developing computational methods to enable the screening of drug-like compounds for intrinsically disordered proteins. Applications will be focused on alpha-synuclein, Abeta and tau, which are three proteins associated with Alzheimer's and Parkinson's diseases. The method will involve the rational design of compounds that bind to structures extracted from ensembles of conformations determined from NMR measurements, using a procedure that was recently developed to represent accurately the dynamics of Intrinsically Disordered Proteins.
Project Home
Michele Vendruscolo
Starting Date October 2011


Intensive Training Module – Marie Curie Training Network
Protein Structure Analysis using NMR Chemical Shifts
May 2012 - Cambridge, United Kingdom

VIZBI 2012 - Visualising Biological Data EMBO Meeting
March, 2012, EMBL, Heidelberg, Germany

Complementary Skills Training – Marie Curie Training Network
Self Marketing, Project Management, Benchmarks and Competition in Research
February 2012 - St. Moritz, Switzerland

Intensive Training Course 2011 – Marie Curie Training Network
Bioinformatics and Structural biology of IDPs
October 2011 - Budapest, Hungary